Aspirin is contraindicated in patients with which of the following conditions?

Aspirin is contraindicated in patients with stomach ulcers because it can exacerbate gastrointestinal issues. Aspirin works as a nonsteroidal anti-inflammatory drug (NSAID) by inhibiting the production of certain substances in the body that promote inflammation, pain, and fever. However, this inhibition also affects the protective mechanisms of the stomach lining, which can lead to increased gastric acid secretion and reduced gastric mucus production.

In individuals who already have stomach ulcers, using aspirin can increase the risk of ulcer-related complications, such as bleeding or perforation. Therefore, healthcare providers typically avoid prescribing aspirin to patients with active peptic ulcers or a history of recurrent ulcers to prevent potentially severe gastrointestinal harm.

Other conditions listed do not have the same direct contraindications associated with aspirin use, making those options less relevant when considering the safety of prescribing aspirin to patients with known medical issues.